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Rabbit anti-Human SRSF8 Polyclonal Antibody

The antibody against SRSF8 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF8 (NP_115285.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00654A

The antibody against SRSF8 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF8 (NP_115285.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00654A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRSF8
Target SynonymsDSM-1; SRP46; SFRS2B; SRSF8FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse kidney, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF8 (NP_115285.1).Target SpeciesHuman
Immunogen SequenceMSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSUniprot IDQ9BRL6
Background Information
  • Uniprot Id

    Q9BRL6

  • Target Species

    Human

  • Target Name

    SRSF8

  • Target Full Name

    Serine/arginine-rich splicing factor 8

  • Target Function

    Involved in pre-mRNA alternative splicing.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Splicing factor SR family

  • Target Tissue Specificity

    Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.

  • Target Synonyms

    SRSF8; SFRS2B; SRP46Serine/arginine-rich splicing factor 8; Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor; arginine/serine-rich 2B

  • Target Background

    This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

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