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The antibody against SSCA1/SerpinB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-390 of human SSCA1/SerpinB3 (NP_008850.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SSCA1/SerpinB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-390 of human SSCA1/SerpinB3 (NP_008850.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-03789A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SSCA1/SerpinB3 |
| Target Synonyms | SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD; SSCA1/SerpinB3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T transfected with SSCA1/SerpinB3 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 2-390 of human SSCA1/SerpinB3 (NP_008850.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P29508 | Immunogen Sequence |
Uniprot Id
P29508
Target Species
Human
Target Name
SERPINB3
Target Full Name
Serpin B3
Target Function
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Target Subcellular Location
Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Target Protein Families
Serpin family, Ov-serpin subfamily
Target Tissue Specificity
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
Target Synonyms
SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD; SSCA1/SerpinB3
Target Background
Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.
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