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The antibody against SSTR4 was raised in rabbit using the Recombinant Human Somatostatin receptor type 4 protein (314-388AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against SSTR4 was raised in rabbit using the Recombinant Human Somatostatin receptor type 4 protein (314-388AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-45137A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SSTR4 |
| Target Synonyms | SSTR4; Somatostatin receptor type 4; SS-4-R; SS4-R; SS4R | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Somatostatin receptor type 4 protein (314-388AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P31391 |
Uniprot Id
P31391
Target Species
Human
Target Name
SSTR4
Target Full Name
Somatostatin receptor type 4
Target Function
Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
Target Synonyms
SSTR4; Somatostatin receptor type 4; SS-4-R; SS4-R; SS4R
Target Background
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.
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