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The antibody against ST8SIA2 was raised in rabbit using the Recombinant Human Alpha-2,8-sialyltransferase 8B protein (24-160AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ST8SIA2 was raised in rabbit using the Recombinant Human Alpha-2,8-sialyltransferase 8B protein (24-160AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human kidney tissue using ST8SIA2 Antibody at dilution of 1:1002
| Cat.No | ADC-43994A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ST8SIA2 |
| Target Synonyms | ST8SIA2 antibody; SIAT8B antibody; STX antibody; Alpha-2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Alpha-2,8-sialyltransferase 8B protein (24-160AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92186 |
Uniprot Id
Q92186
Target Species
Human
Target Name
ST8SIA2
Target Full Name
Alpha-2,8-sialyltransferase 8B
Target Function
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 29 family
Target Tissue Specificity
Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
Target Synonyms
ST8SIA2; SIAT8B; STX; Alpha-2,8-sialyltransferase 8B; EC 2.4.99.-; Sialyltransferase 8B; SIAT8-B; Sialyltransferase St8Sia II; ST8SiaII; Sialyltransferase X; STX
Target Background
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.
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