Rabbit anti-Human STK16 Polyclonal Antibody

Uniprot Id

O75716

Target Species

Human

Target Name

STK16

Target Full Name

Serine/threonine-protein kinase 16

Target Function

Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

Target Subcellular Location

Cytoplasm, perinuclear region. Membrane; Lipid-anchor.

Target Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family

Target Tissue Specificity

Ubiquitously expressed at very low levels.

Target Research Area

Signal Transduction

Target Synonyms

EDPK; F52; FLJ39635; hPSK; KRCT; MGC16211; MPSK; MPSK1; Myristoylated and palmitoylated serine/threonine protein kinase; Myristoylated and palmitoylated serine/threonine-protein kinase; PKL12 ; Protein kinase expressed in day 12 fetal liver ; Protein kinase Krct; Protein kinase PKL12; Serine/threonine kinase 16 ; Serine/threonine protein kinase 16; Serine/threonine-protein kinase 16; Stk16; STK16_HUMAN; TGF beta stimulated factor 1; TGF-beta-stimulated factor 1; TGFB stimulated factor 1; Transforming growth factor beta stimulated factor 1; TSF-1; TSF1; Tyrosine protein kinase STK16

Target Background

Predicted to enable protein serine/threonine kinase activity. Involved in protein autophosphorylation. Located in cytosol; nucleoplasm; and plasma membrane.