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Rabbit anti-Human SUPT20H Polyclonal Antibody

The antibody against SUPT20H was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 580-779 of human SUPT20H (NP_001014308.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-02548A

The antibody against SUPT20H was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 580-779 of human SUPT20H (NP_001014308.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-02548A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSUPT20H
Target SynonymsC13; FP757; P38IP; SPT20; FAM48A; C13orf19; SUPT20HFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, HL-60, Mouse brain, Mouse lung, Mouse testis, Rat kidney, SW480ApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 580-779 of human SUPT20H (NP_001014308.2).Target SpeciesHuman
Immunogen SequenceNLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQQIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKFUniprot IDQ8NEM7
Background Information
  • Uniprot Id

    Q8NEM7

  • Target Species

    Human

  • Target Name

    SUPT20H

  • Target Full Name

    Transcription factor SPT20 homolog

  • Target Function

    Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SPT20 family

  • Target Tissue Specificity

    Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.

  • Target Synonyms

    AA667204; AI450544; bA421P11.4; C13; C13orf19; D3Ertd300e; FA48A_HUMAN; FAM48A; FP757; p38-interacting protein; p38IP; Protein FAM48A; RGD1307812; SPT20

  • Target Background

    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of gluconeogenesis and positive regulation of transcription by RNA polymerase II. Part of SAGA-type complex.

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