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The antibody against SUSD4 was raised in rabbit using the Recombinant Human Sushi domain-containing protein 4 protein (56-290AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against SUSD4 was raised in rabbit using the Recombinant Human Sushi domain-containing protein 4 protein (56-290AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-23375A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SUSD4 |
| Target Synonyms | SUSD4 antibody; UNQ196/PRO222 antibody; Sushi domain-containing protein 4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sushi domain-containing protein 4 protein (56-290AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VX71 |
Uniprot Id
Q5VX71
Target Species
Human
Target Name
SUSD4
Target Full Name
Sushi domain-containing protein 4
Target Function
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
Target Subcellular Location
[Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
Target Tissue Specificity
Isoform 3 is the predominant isoform in all tissues except cortex, cerebellum, kidney, and breast. Isoform 1 is found primarily in the esophagus and the brain.
Target Synonyms
SUSD4; UNQ196/PRO222; Sushi domain-containing protein 4
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