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The antibody against SV2A was raised in rabbit using the Recombinant Human Synaptic vesicle glycoprotein 2A protein (36-149AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SV2A was raised in rabbit using the Recombinant Human Synaptic vesicle glycoprotein 2A protein (36-149AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using SV2A Antibody at dilution of 1:100
| Cat.No | ADC-09120A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SV2A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Synaptic vesicle glycoprotein 2A protein (36-149AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7L0J3 |
Uniprot Id
Q7L0J3
Target Species
Human
Target Name
SV2A
Target Full Name
Synaptic vesicle glycoprotein 2A
Target Function
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.
Target Subcellular Location
Cell junction, synapse, presynapse. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator superfamily
Target Synonyms
KIAA0736; OTTHUMP00000014065; SV2; Sv2a; SV2A_HUMAN; Synaptic vesicle glycoprotein 2; Synaptic vesicle glycoprotein 2A; Synaptic vesicle protein 2a
Target Background
The protein encoded by this gene is one of three related synaptic vesicle proteins. The encoded protein may interact with synaptotagmin to enhance low frequency neurotransmission in quiescent neurons.
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