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The antibody against SV2C was raised in rabbit using the Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SV2C was raised in rabbit using the Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-05015A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SV2C |
| Target Synonyms | SV2C antibody; KIAA1054 antibody; Synaptic vesicle glycoprotein 2C antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Synaptic vesicle glycoprotein 2C protein (459-524AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q496J9 |
Uniprot Id
Q496J9
Target Species
Human
Target Name
SV2C
Target Full Name
Synaptic vesicle glycoprotein 2C
Target Function
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4. Recognition by BoNT/A relies on both protein-protein and protein-N-glycosylation; glycosylation of Asn-559 increases its affinity for BoNT/A. Also serves as a receptor for the closely related C.botulinum neurotoxin type A2; glycosylation is not essential but enhances the interaction.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); note that type D does not usually infect humans.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator superfamily
Target Synonyms
SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C
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