Rabbit anti-Human SYCP3 Polyclonal Antibody

The antibody against SYCP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SYCP3 (NP_710161.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00962A

Number

Cat.No	ADA-00962A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SYCP3
Target Synonyms	COR1; SCP3; SPGF4; RPRGL4; SYCP3	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse ovary, Rat ovary	Application	ELISA, WB

Cat.No

ADA-00962A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SYCP3

Target Synonyms

COR1; SCP3; SPGF4; RPRGL4; SYCP3

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse ovary, Rat ovary

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SYCP3 (NP_710161.1).	Target Species	Human
Uniprot ID	Q8IZU3	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SYCP3 (NP_710161.1).

Target Species

Human

Uniprot ID

Q8IZU3

Immunogen Sequence

Background Information

Uniprot Id

Q8IZU3
Target Species

Human
Target Name

SYCP3
Target Full Name

Synaptonemal complex protein 3
Target Function

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2.
Target Involvement

Spermatogenic failure 4 (SPGF4); Pregnancy loss, recurrent, 4 (RPRGL4)
Target Subcellular Location

Nucleus. Chromosome. Chromosome, centromere.
Target Protein Families

XLR/SYCP3 family
Target Tissue Specificity

Testis-specific.
Target Synonyms

choline phosphotransferase 1; chpt1; COR 1; COR1; MGC71888; RNASCP3; SCP 3; SCP-3; SCP3; SPGF4; Sycp 3; Sycp3; SYCP3_HUMAN; Synaptonemal complex protein 3
Target Background

This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

Rabbit anti-Human SYCP3 Polyclonal Antibody

Specifications

Immunogen Information

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