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The antibody against SYP was raised in rabbit using the Peptide sequence around aa.305~309(A-P-T-S-F) derived from Human Synaptophysin as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
The antibody against SYP was raised in rabbit using the Peptide sequence around aa.305~309(A-P-T-S-F) derived from Human Synaptophysin as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from Rat and Mouse brain tissue and C6 cells using Synaptophysin Antibody.
| Cat.No | ADC-43134A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SYP |
| Target Synonyms | SYP; Synaptophysin; Major synaptic vesicle protein p38 | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa.305~309(A-P-T-S-F) derived from Human Synaptophysin | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P08247 |
Uniprot Id
P08247
Target Species
Human
Target Name
SYP
Target Full Name
Synaptophysin
Target Function
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Target Involvement
Mental retardation, X-linked 96 (MRX96)
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Target Protein Families
Synaptophysin/synaptobrevin family
Target Tissue Specificity
Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3.
Target Research Area
Neuroscience
Target Synonyms
SYP; Synaptophysin; Major synaptic vesicle protein p38
Target Background
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
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