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The antibody against SYT10 was raised in rabbit using the Recombinant Human Synaptotagmin-10 protein (301-523AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SYT10 was raised in rabbit using the Recombinant Human Synaptotagmin-10 protein (301-523AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human ovarian cancer using SYT10 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using SYT10 Antibody at dilution of 1:1002
| Cat.No | ADC-19637A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SYT10 |
| Target Synonyms | Synaptotagmin X antibody; Synaptotagmin-10 antibody; SYT10 antibody; SYT10_HUMAN antibody; SytX antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Synaptotagmin-10 protein (301-523AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6XYQ8 |
Uniprot Id
Q6XYQ8
Target Species
Human
Target Name
SYT10
Target Full Name
Synaptotagmin-10
Target Function
Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis. Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.
Target Protein Families
Synaptotagmin family
Target Tissue Specificity
Expressed only in pancreas, lung and kidney.
Target Synonyms
Synaptotagmin X; Synaptotagmin-10; SYT10; SYT10_HUMAN; SytX
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