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The antibody against SYT3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SYT3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07096A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SYT3 |
| Target Synonyms | SytIII; SYT3 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 449-590 of human SYT3 (NP_115674.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE | Uniprot ID | Q9BQG1 |
Uniprot Id
Q9BQG1
Target Species
Human
Target Name
SYT3
Target Full Name
Synaptotagmin-3
Target Function
Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes.
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.
Target Protein Families
Synaptotagmin family
Target Tissue Specificity
Expressed in melanocytes.
Target Synonyms
SytIII; SYT3
Target Background
Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Involved in positive regulation of dendrite extension. Located in endosome.
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