Rabbit anti-Human TACC3 Monoclonal Antibody

The antibody against TACC3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human TACC3 (NP_006333.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-14388A

Number

Cat.No	ADA-14388A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	TACC3
Target Synonyms	ERIC1; Tacc4; ERIC-1; maskin; TACC3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-14388A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

TACC3

Target Synonyms

ERIC1; Tacc4; ERIC-1; maskin; TACC3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TACC3 (NP_006333.1).	Target Species	Human
Immunogen Sequence	MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTPLRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQK	Uniprot ID	Q9Y6A5

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TACC3 (NP_006333.1).

Target Species

Human

Immunogen Sequence

MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTPLRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQK

Uniprot ID

Q9Y6A5

Background Information

Uniprot Id

Q9Y6A5
Target Species

Human
Target Name

TACC3
Target Full Name

Transforming acidic coiled-coil-containing protein 3
Target Function

Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. May be involved in the control of cell growth and differentiation. May contribute to cancer.
Target Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families

TACC family
Target Synonyms

ERIC 1; ERIC-1; ERIC1; MGC117382; MGC133242; OTTHUMP00000113796; TACC3; TACC3_HUMAN; Transforming acidic coiled coil containing protein 3; Transforming acidic coiled-coil-containing protein 3
Target Background

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.

Rabbit anti-Human TACC3 Monoclonal Antibody

Specifications

Immunogen Information

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