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The antibody against TALDO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-337 of human TALDO1 (NP_006746.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TALDO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-337 of human TALDO1 (NP_006746.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02855A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TALDO1 |
| Target Synonyms | TAL; TALH; TAL-H; TALDOR; TALDO1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-431, Mouse brain, SW480 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-337 of human TALDO1 (NP_006746.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P37837 | Immunogen Sequence |
Uniprot Id
P37837
Target Species
Human
Target Name
TALDO1
Target Full Name
Transaldolase
Target Function
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Target Involvement
Transaldolase deficiency (TALDOD)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Transaldolase family, Type 1 subfamily
Target Research Area
Metabolism
Target Synonyms
Dihydroxyacetone transferase; EC 2.2.1.2; EPS8L2 ; Glycerone transferase ; TAL; TAL H; TALDO; TALDO_HUMAN; TALDO1; TALDOR ; TALH ; Transaldolase 1; Transaldolase
Target Background
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
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