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The antibody against TBC1D1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1069-1168 of human TBC1D1 (NP_055988.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TBC1D1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1069-1168 of human TBC1D1 (NP_055988.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00972A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBC1D1 |
| Target Synonyms | TBC; TBC1; TBC1D1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse testis, Rat testis | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1069-1168 of human TBC1D1 (NP_055988.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD | Uniprot ID | Q86TI0 |
Uniprot Id
Q86TI0
Target Species
Human
Target Name
TBC1D1
Target Full Name
TBC1 domain family member 1
Target Function
May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells.
Target Subcellular Location
Nucleus.
Target Synonyms
KIAA1108; TBC 1; TBC; TBC1 (tre 2/USP6; BUB2; cdc16) domain family; member 1; TBC1; TBC1 domain family member 1; Tbc1d1; TBCD1_HUMAN
Target Background
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).
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