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The antibody against TBCA was raised in rabbit using the Recombinant Human Tubulin-specific chaperone A protein (2-108AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against TBCA was raised in rabbit using the Recombinant Human Tubulin-specific chaperone A protein (2-108AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate cancer using TBCA Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using TBCA Antibody at dilution of 1:1002
| Cat.No | ADC-23346A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBCA |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tubulin-specific chaperone A protein (2-108AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75347 |
Uniprot Id
O75347
Target Species
Human
Target Name
TBCA
Target Full Name
Tubulin-specific chaperone A
Target Function
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
TBCA family
Target Synonyms
CFA; Chaperonin cofactor A; Co chaperonin associated with a & b tubulin; Cofactor A; tbca; TBCA_HUMAN; TCP1 chaperonin cofactor A; TCP1-chaperonin cofactor A; Tubulin cofactor a; Tubulin folding cofactor A; Tubulin specific chaperone a; Tubulin-folding cofactor A; Tubulin-specific chaperone A
Target Background
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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