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The antibody against TBCC was raised in rabbit using the Recombinant Human Tubulin-specific chaperone C protein (2-346AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against TBCC was raised in rabbit using the Recombinant Human Tubulin-specific chaperone C protein (2-346AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using TBCC Antibody at dilution of 1:1002
| Cat.No | ADC-50626A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBCC |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tubulin-specific chaperone C protein (2-346AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15814 |
Uniprot Id
Q15814
Target Species
Human
Target Name
TBCC
Target Full Name
Tubulin-specific chaperone C
Target Function
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
Target Subcellular Location
Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium.
Target Protein Families
TBCC family
Target Tissue Specificity
Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecti
Target Research Area
Signal Transduction
Target Synonyms
Beta tubulin cofactor C; CFC; TBCC; TBCC_HUMAN; Tubulin folding cofactor C; Tubulin specific chaperone c; Tubulin-folding cofactor C; Tubulin-specific chaperone C
Target Background
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
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