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The antibody against TBRG1 was raised in rabbit using the Recombinant Human Transforming growth factor beta regulator 1 protein (22-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TBRG1 was raised in rabbit using the Recombinant Human Transforming growth factor beta regulator 1 protein (22-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using TBRG1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using TBRG1 Antibody at dilution of 1:1002
| Cat.No | ADC-44498A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBRG1 |
| Target Synonyms | TBRG1 antibody; NIAM antibody; Transforming growth factor beta regulator 1 antibody; Nuclear interactor of ARF and Mdm2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transforming growth factor beta regulator 1 protein (22-150AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q3YBR2 |
Uniprot Id
Q3YBR2
Target Species
Human
Target Name
TBRG1
Target Full Name
Transforming growth factor beta regulator 1
Target Function
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
Target Subcellular Location
Nucleus.
Target Protein Families
TBRG1 family
Target Tissue Specificity
Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell
Target Synonyms
TBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2
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