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The antibody against TBX20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TBX20 (NP_001071121.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against TBX20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TBX20 (NP_001071121.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-10023A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBX20 |
| Target Synonyms | ASD4; TBX20 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TBX20 (NP_001071121.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UMR3 | Immunogen Sequence |
Uniprot Id
Q9UMR3
Target Species
Human
Target Name
TBX20
Target Full Name
T-box transcription factor TBX20
Target Function
Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart.
Target Involvement
Atrial septal defect 4 (ASD4)
Target Subcellular Location
Nucleus.
Target Synonyms
T-box 20; T-box protein 20; T-box transcription factor TBX20; Tbox 20; tbx20; TBX20_HUMAN
Target Background
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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