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The antibody against TCEAL7 was raised in rabbit using the Recombinant Human Transcription elongation factor A protein-like 7 protein (1-100AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against TCEAL7 was raised in rabbit using the Recombinant Human Transcription elongation factor A protein-like 7 protein (1-100AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using TCEAL7 Antibody at dilution of 1:1002
| Cat.No | ADC-23340A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TCEAL7 |
| Target Synonyms | TCEAL7 antibody; Transcription elongation factor A protein-like 7 antibody; TCEA-like protein 7 antibody; Transcription elongation factor S-II protein-like 7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription elongation factor A protein-like 7 protein (1-100AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BRU2 |
Uniprot Id
Q9BRU2
Target Species
Human
Target Name
TCEAL7
Target Full Name
Transcription elongation factor A protein-like 7
Target Function
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
Target Subcellular Location
Nucleus.
Target Protein Families
TFS-II family, TFA subfamily
Target Tissue Specificity
Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors.
Target Synonyms
TCEAL7; Transcription elongation factor A protein-like 7; TCEA-like protein 7; Transcription elongation factor S-II protein-like 7
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