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The antibody against TCERG1 was raised in rabbit using the Recombinant Human Transcription elongation regulator 1 protein (782-896AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against TCERG1 was raised in rabbit using the Recombinant Human Transcription elongation regulator 1 protein (782-896AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04203A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TCERG1 |
| Target Synonyms | RNA polymerase II | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription elongation regulator 1 protein (782-896AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14776 |
Uniprot Id
O14776
Target Species
Human
Target Name
TCERG1
Target Full Name
Transcription elongation regulator 1
Target Function
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Detected in brain neurons.
Target Synonyms
CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated factor 2S; TATA box binding protein associated factor RNA polymerase II S 150kD; TATA box-binding protein-associated factor 2S; TBP-associated factor, RNA polymerase II, 150-kD; TCERG 1; TCERG1; TCRG1_HUMAN; Transcription elongation regulator 1; Transcription factor CA 150; Transcription factor CA150; Urn1
Target Background
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
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