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The antibody against TCF15 was raised in rabbit using the Recombinant Human Transcription factor 15 protein (24-199AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against TCF15 was raised in rabbit using the Recombinant Human Transcription factor 15 protein (24-199AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-09067A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TCF15 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor 15 protein (24-199AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q12870 |
Uniprot Id
Q12870
Target Species
Human
Target Name
TCF15
Target Full Name
Transcription factor 15
Target Function
Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency. Essential for the mesenchymal to epithelial transition associated with somite formation. Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and skeletal muscles. Required for proper localization of somite epithelium markers during the mesenchymal to epithelial transition. Also plays a key role in regulation of stem cell pluripotency. Promotes pluripotency exit of embryonic stem cells (ESCs) by priming ESCs for differentiation. Acts as a key regulator of self-renewal of hematopoietic stem cells (HSCs) by mediating HSCs quiescence and long-term self-renewal. Together with MEOX2, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. Acts by forming a heterodimer with another helix-loop-helix (bHLH) protein, such as TCF3/E12, that binds DNA on E-box motifs (5'-CANNTG-3') and activates transcription of target genes.
Target Subcellular Location
Nucleus.
Target Synonyms
bHLH EC2 protein; bHLHa40; BHLHEC2; Class A basic helix-loop-helix protein 40; EC2; Paraxis; Protein bHLH-EC2; TCF-15; Tcf15; TCF15_HUMAN; Transcription factor 15
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