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The antibody against TES was raised in rabbit using the Recombinant Human Testin protein (130-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against TES was raised in rabbit using the Recombinant Human Testin protein (130-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-03774A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TES |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Testin protein (130-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UGI8 |
Uniprot Id
Q9UGI8
Target Species
Human
Target Name
TES
Target Full Name
Testin
Target Function
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.
Target Subcellular Location
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Target Protein Families
Prickle / espinas / testin family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
DKFZP586B2022; MGC1146; TES; TES_HUMAN; TESS 2; TESS; TESS2; Testin; Testis derived transcript (3 LIM domains); Testis derived transcript
Target Background
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
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