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The antibody against TESK2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TESK2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against TESK2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TESK2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of HeLa cells using TESK2 Polyclonal Antibody
| Cat.No | ADC-37490A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TESK2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human TESK2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96S53 |
Uniprot Id
Q96S53
Target Species
Human
Target Name
TESK2
Target Full Name
Dual specificity testis-specific protein kinase 2
Target Function
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Target Subcellular Location
Nucleus.
Target Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family
Target Tissue Specificity
Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells.
Target Synonyms
Dual specificity testis specific protein kinase 2; Dual specificity testis-specific protein kinase 2; MGC29168; OTTHUMP00000009093; RP23-109A3.2; Tesk2; TESK2_HUMAN; Testicular protein kinase 2; Testis specific kinase 2
Target Background
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants.
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