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The antibody against TESPA1 was raised in rabbit using the Recombinant Human Protein TESPA1 protein (251-521AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TESPA1 was raised in rabbit using the Recombinant Human Protein TESPA1 protein (251-521AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using TESPA1 Antibody at dilution of 1:100
Immunofluorescent analysis of A549 cells using TESPA1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-21963A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TESPA1 |
| Target Synonyms | TESPA1 antibody; KIAA0748 antibody; HSPC257Protein TESPA1 antibody; Thymocyte-expressed positive selection-associated protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein TESPA1 protein (251-521AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A2RU30 |
Uniprot Id
A2RU30
Target Species
Human
Target Name
TESPA1
Target Full Name
Protein TESPA1
Target Function
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum membrane.
Target Synonyms
TESPA1; KIAA0748; HSPC257Protein TESPA1; Thymocyte-expressed positive selection-associated protein 1
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