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The antibody against TFEC was raised in rabbit using the Recombinant Human Transcription factor EC protein (1-197AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against TFEC was raised in rabbit using the Recombinant Human Transcription factor EC protein (1-197AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-22390A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TFEC |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor EC protein (1-197AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14948 |
Uniprot Id
O14948
Target Species
Human
Target Name
TFEC
Target Full Name
Transcription factor EC
Target Function
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Target Subcellular Location
Nucleus.
Target Protein Families
MiT/TFE family
Target Tissue Specificity
Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
Target Synonyms
bHLHe34; Class E basic helix-loop-helix protein 34; hTFEC-L; TCFEC; TFE-C; Tfec; TFEC protein; TFEC_HUMAN; TFECL; Transcription factor EC; Transcription factor EC-like
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