Rabbit anti-Human TGF beta induced (TGFBI) Polyclonal Antibody

The antibody against TGF beta induced (TGFBI) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_000349.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01751A

Number

Cat.No	ADA-01751A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TGF beta induced (TGFBI)
Target Synonyms	CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1; TGF beta induced (TGFBI)	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse eye, Mouse spleen, SKOV3	Application	ELISA, WB

Cat.No

ADA-01751A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TGF beta induced (TGFBI)

Target Synonyms

CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1; TGF beta induced (TGFBI)

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse eye, Mouse spleen, SKOV3

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_000349.1).	Target Species	Human
Immunogen Sequence	LPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSA	Uniprot ID	Q15582

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_000349.1).

Target Species

Human

Immunogen Sequence

LPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSA

Uniprot ID

Q15582

Background Information

Uniprot Id

Q15582
Target Species

Human
Target Name

TGFBI
Target Full Name

Transforming growth factor-beta-induced protein ig-h3
Target Function

Plays a role in cell adhesion. May play a role in cell-collagen interactions.
Target Involvement

Corneal dystrophy, epithelial basement membrane (EBMD); Corneal dystrophy, Groenouw type 1 (CDGG1); Corneal dystrophy, lattice type 1 (CDL1); Corneal dystrophy, Thiel-Behnke type (CDTB); Corneal dystrophy, Reis-Bucklers type (CDRB); Corneal dystrophy, lattice type 3A (CDL3A); Corneal dystrophy, Avellino type (CDA)
Target Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix.
Target Tissue Specificity

Highly expressed in the corneal epithelium. Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms

RGD containing collagen associated protein; AI181842; AI747162; Beta ig; Beta ig h3; Beta ig-h3; BGH3_HUMAN; Big h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; Kerato epithelin; Kerato-epithelin; LCD1; MGC150270; RGD CAP; RGD-CAP; RGD-containing collagen-associated protein; TGFBI; TGFBI transforming growth factor, beta induced, 68kDa; Transforming growth factor beta induced protein ig h3; Transforming growth factor-beta-induced protein ig-h3
Target Background

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Rabbit anti-Human TGF beta induced (TGFBI) Polyclonal Antibody

Specifications

Immunogen Information

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