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The antibody against THAP12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human THAP12 (NP_004696.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against THAP12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human THAP12 (NP_004696.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05283A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | THAP12 |
| Target Synonyms | DAP4; THAP0; PRKRIR; P52rIPK; THAP12 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain, SH-SY5Y | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human THAP12 (NP_004696.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43422 | Immunogen Sequence |
Uniprot Id
O43422
Target Species
Human
Target Name
THAP12
Target Full Name
52 kDa repressor of the inhibitor of the protein kinase
Target Function
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
Target Research Area
Signal Transduction
Target Synonyms
THAP12; DAP4; P52RIPK; PRKRIR; THAP0; 52 kDa repressor of the inhibitor of the protein kinase; p52rIPK; 58 kDa interferon-induced protein kinase-interacting protein; p58IPK-interacting protein; Death-associated protein 4; THAP domain-containing protein 0; THAP domain-containing protein 12
Target Background
Predicted to enable DNA binding activity; metal ion binding activity; and protein dimerization activity. Predicted to be involved in negative regulation of cell population proliferation and signal transduction. Predicted to be located in nucleus.
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