Rabbit anti-Human THRA Polyclonal Antibody

The antibody against THRA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 138-180 of human THRA (NP_003241.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03741A

Number

Cat.No	ADA-03741A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	THRA
Target Synonyms	AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; c-erbA; ERB-T-1; TRalpha; THRalpha; TRalpha1; TRalpha2; c-ERBA-1; THRalpha1; THRalpha2; THRA	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	SH-SY5Y	Application	ELISA, WB, IHC-P

Cat.No

ADA-03741A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

THRA

Target Synonyms

AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; c-erbA; ERB-T-1; TRalpha; THRalpha; TRalpha1; TRalpha2; c-ERBA-1; THRalpha1; THRalpha2; THRA

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

SH-SY5Y

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 138-180 of human THRA (NP_003241.2).	Target Species	Human
Immunogen Sequence	IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA	Uniprot ID	P10827

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 138-180 of human THRA (NP_003241.2).

Target Species

Human

Immunogen Sequence

IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNA

Uniprot ID

P10827

Background Information

Uniprot Id

P10827
Target Species

Human
Target Name

THRA
Target Full Name

Thyroid hormone receptor alpha
Target Function

Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
Target Involvement

Hypothyroidism, congenital, non-goitrous, 6 (CHNG6)
Target Subcellular Location

Nucleus.; [Isoform Alpha-2]: Cytoplasm. Nucleus.
Target Protein Families

Nuclear hormone receptor family, NR1 subfamily
Target Research Area

Neuroscience
Target Synonyms

c-erbA-1; C-erbA-alpha; EAR-7; ERBA 1; ERBA; ERBA related 7; Nuclear receptor subfamily 1 group A member 1; THA_HUMAN; THRA; Thra1; Thra2; Thyroid hormone receptor alpha 1; Thyroid hormone receptor alpha 2; Thyroid hormone receptor alpha; TR alpha 1; TR alpha 2; Tra1; Triiodothyronine receptor; V-erbA-related protein 7
Target Background

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Rabbit anti-Human THRA Polyclonal Antibody

Specifications

Immunogen Information

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