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The antibody against TINAGL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 258-467 of human TINAGL1 (NP_071447.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TINAGL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 258-467 of human TINAGL1 (NP_071447.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-03446A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TINAGL1 |
| Target Synonyms | ARG1; LCN7; LIECG3; TINAGRP; TINAGL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 258-467 of human TINAGL1 (NP_071447.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9GZM7 | Immunogen Sequence |
Uniprot Id
Q9GZM7
Target Species
Human
Target Name
TINAGL1
Target Full Name
Tubulointerstitial nephritis antigen-like
Target Function
May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase C1 family
Target Tissue Specificity
Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary,
Target Synonyms
TINAGL1; GIS5; LCN7; OLRG2; TINAGL; PP6614; PSEC0088; UNQ204/PRO230; Tubulointerstitial nephritis antigen-like; Glucocorticoid-inducible protein 5; Oxidized LDL-responsive gene 2 protein; OLRG-2; Tubulointerstitial nephritis antigen-related protein; TIN Ag-related protein; TIN-Ag-RP
Target Background
The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene.
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