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The antibody against TINAGL1 was raised in rabbit using the Recombinant Human Tubulointerstitial nephritis antigen-like protein (250-467AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TINAGL1 was raised in rabbit using the Recombinant Human Tubulointerstitial nephritis antigen-like protein (250-467AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human placenta tissue using TINAGL1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using TINAGL1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-18162A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TINAGL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tubulointerstitial nephritis antigen-like protein (250-467AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZM7 |
Uniprot Id
Q9GZM7
Target Species
Human
Target Name
TINAGL1
Target Full Name
Tubulointerstitial nephritis antigen-like
Target Function
May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase C1 family
Target Tissue Specificity
Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary,
Target Synonyms
TINAGL1; GIS5; LCN7; OLRG2; TINAGL; PP6614; PSEC0088; UNQ204/PRO230; Tubulointerstitial nephritis antigen-like; Glucocorticoid-inducible protein 5; Oxidized LDL-responsive gene 2 protein; OLRG-2; Tubulointerstitial nephritis antigen-related protein; TIN Ag-related protein; TIN-Ag-RP
Target Background
The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene.
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