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The antibody against TIPARP was raised in rabbit using the Synthetic peptide of Human TIPARP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against TIPARP was raised in rabbit using the Synthetic peptide of Human TIPARP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-54587A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TIPARP |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human TIPARP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z3E1 |
Uniprot Id
Q7Z3E1
Target Species
Human
Target Name
TIPARP
Target Full Name
Protein mono-ADP-ribosyltransferase TIPARP
Target Function
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.
Target Subcellular Location
Nucleus.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; AW558171; DDF1; DKFZp434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP 1; PARP 7; PARP-7; PARPT_HUMAN; pART14; Poly [ADP ribose] polymerase 7; Poly [ADP-ribose] polymerase 7; TCDD inducible poly(ADP ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; TIPARP
Target Background
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.
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