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The antibody against TM7SF3 was raised in rabbit using the Recombinant Human Transmembrane 7 superfamily member 3 protein (22-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TM7SF3 was raised in rabbit using the Recombinant Human Transmembrane 7 superfamily member 3 protein (22-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using TM7SF3 Antibody at dilution of 1:100
Immunofluorescent analysis of U251 cells using TM7SF3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-23291A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TM7SF3 |
| Target Synonyms | TM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane protein | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transmembrane 7 superfamily member 3 protein (22-295AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NS93 |
Uniprot Id
Q9NS93
Target Species
Human
Target Name
TM7SF3
Target Full Name
Transmembrane 7 superfamily member 3
Target Function
Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR).
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Tissue Specificity
Widely expressed. Highly expressed in kidney and pancreas.
Target Synonyms
TM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane protein
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