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Rabbit anti-Human TM7SF3 Polyclonal Antibody

The antibody against TM7SF3 was raised in rabbit using the Human TM7SF3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51578A

The antibody against TM7SF3 was raised in rabbit using the Human TM7SF3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51578A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTM7SF3
Target SynonymsTM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane proteinFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman TM7SF3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NS93
Background Information
  • Uniprot Id

    Q9NS93

  • Target Species

    Human

  • Target Name

    TM7SF3

  • Target Full Name

    Transmembrane 7 superfamily member 3

  • Target Function

    Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR).

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Tissue Specificity

    Widely expressed. Highly expressed in kidney and pancreas.

  • Target Synonyms

    TM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane protein

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