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The antibody against TMBIM1 was raised in rabbit using the Recombinant Human Protein lifeguard 3 protein (1-109AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against TMBIM1 was raised in rabbit using the Recombinant Human Protein lifeguard 3 protein (1-109AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-23287A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMBIM1 |
| Target Synonyms | TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein lifeguard 3 protein (1-109AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969X1 |
Uniprot Id
Q969X1
Target Species
Human
Target Name
TMBIM1
Target Full Name
Protein lifeguard 3
Target Function
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
Target Protein Families
BI1 family, LFG subfamily
Target Synonyms
TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1
Target Background
Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane.
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