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The antibody against TMBIM1 was raised in rabbit using the Synthesized peptide derived from internal of Human TMBIM1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against TMBIM1 was raised in rabbit using the Synthesized peptide derived from internal of Human TMBIM1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HuvEc cells, using TMBIM1 antibody.
| Cat.No | ADC-40850A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMBIM1 |
| Target Synonyms | TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human TMBIM1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969X1 |
Uniprot Id
Q969X1
Target Species
Human
Target Name
TMBIM1
Target Full Name
Protein lifeguard 3
Target Function
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
Target Protein Families
BI1 family, LFG subfamily
Target Synonyms
TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1
Target Background
Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane.
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