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The antibody against TMC1 was raised in rabbit using the Human TMC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against TMC1 was raised in rabbit using the Human TMC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-46916A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMC1 |
| Target Synonyms | TMC1; Transmembrane channel-like protein 1; Transmembrane cochlear-expressed protein 1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TMC1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TDI8 |
Uniprot Id
Q8TDI8
Target Species
Human
Target Name
TMC1
Target Full Name
Transmembrane channel-like protein 1
Target Function
Probable ion channel required for the normal function of cochlear hair cells.
Target Involvement
Deafness, autosomal dominant, 36 (DFNA36); Deafness, autosomal recessive, 7 (DFNB7)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
TMC family
Target Tissue Specificity
Detected in fetal cochlea, and at low levels in placenta and testis.
Target Synonyms
TMC1; Transmembrane channel-like protein 1; Transmembrane cochlear-expressed protein 1
Target Background
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.
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