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The antibody against TMEM108 was raised in rabbit using the Human TMEM108 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against TMEM108 was raised in rabbit using the Human TMEM108 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-45853A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMEM108 |
| Target Synonyms | TMEM108 antibody; KIAA1690 antibody; RTLN antibody; UNQ1875/PRO4318 antibody; Transmembrane protein 108 antibody; Retrolinkin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TMEM108 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UXF1 |
Uniprot Id
Q6UXF1
Target Species
Human
Target Name
TMEM108
Target Full Name
Transmembrane protein 108
Target Function
Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density. Endosome membrane. Cell projection, axon. Cell projection, dendrite. Early endosome.
Target Synonyms
TMEM108; KIAA1690; RTLN; UNQ1875/PRO4318; Transmembrane protein 108; Retrolinkin
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