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The antibody against TMEM126A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human TMEM126A (NP_115649.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TMEM126A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human TMEM126A (NP_115649.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09549A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TMEM126A |
| Target Synonyms | OPA7; TMEM126A | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 22Rv1, Rat ovary | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human TMEM126A (NP_115649.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MENHKSNNKENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH | Uniprot ID | Q9H061 |
Uniprot Id
Q9H061
Target Species
Human
Target Name
TMEM126A
Target Full Name
Transmembrane protein 126A
Target Involvement
Optic atrophy 7 with or without auditory neuropathy (OPA7)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
TMEM126 family
Target Tissue Specificity
Strongly expressed in brain, cerebellum, skeletal muscle, testis. High expression also found in fetal brain, fetal retinal pigmentary epithelium, and fetal retina. Highly expressed in retinal ganglion cells.
Target Synonyms
TMEM126A; Transmembrane protein 126A
Target Background
The protein encoded by this gene is a mitochondrial membrane protein of unknown function. Defects in this gene are a cause of optic atrophy type 7 (OPA7). Two transcript variants encoding different isoforms have been found for this gene.
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