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The antibody against TMPRSS15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human TMPRSS15 (NP_002763.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TMPRSS15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human TMPRSS15 (NP_002763.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01348A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Tmprss15 |
| Target Synonyms | ENTK; PRSS7; TMPRSS15 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | BT-474, HT-1080, HT-29, Jurkat, Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human TMPRSS15 (NP_002763.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P98073 | Immunogen Sequence |
Uniprot Id
P98073
Target Species
Human
Target Name
TMPRSS15
Target Full Name
Enteropeptidase
Target Function
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
Target Involvement
Enterokinase deficiency (ENTKD)
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Intestinal brush border.
Target Synonyms
TMPRSS15; ENTK; PRSS7; Enteropeptidase; Enterokinase; Serine protease 7; Transmembrane protease serine 15
Target Background
This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
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