Rabbit anti-Human TNFRSF17 Polyclonal Antibody

The antibody against TNFRSF17 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-06762A

Number

Cat.No	ADA-06762A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TNFRSF17
Target Synonyms	BCM; BCMA; CD269; TNFRSF13A; TNFRSF17	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	Raji, Rat spleen, SP2/0	Application	ELISA, WB, IF/ICC

Cat.No

ADA-06762A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TNFRSF17

Target Synonyms

BCM; BCMA; CD269; TNFRSF13A; TNFRSF17

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

Raji, Rat spleen, SP2/0

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2).	Target Species	Human
Immunogen Sequence	MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMA	Uniprot ID	Q02223

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNFRSF17 (NP_001183.2).

Target Species

Human

Immunogen Sequence

MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMA

Uniprot ID

Q02223

Background Information

Uniprot Id

Q02223
Target Species

Human
Target Name

TNFRSF17
Target Full Name

Tumor necrosis factor receptor superfamily member 17
Target Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Target Involvement

A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Target Subcellular Location

Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Target Tissue Specificity

Expressed in mature B-cells, but not in T-cells or monocytes.
Target Research Area

Cancer
Target Synonyms

BCM; BCMA; CD269; TNFRSF13A; TNFRSF17
Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Rabbit anti-Human TNFRSF17 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human TNFRSF17 Polyclonal Antibody Now

Related Products