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The antibody against TNKS1BP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against TNKS1BP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
Immunohistochemistry analysis of paraffin-embedded human colon using TNKS1BP1 Rabbit pAb at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
| Cat.No | ADA-00388A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TNKS1BP1 |
| Target Synonyms | TAB182; TNKS1BP1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9C0C2 | Immunogen Sequence |
Uniprot Id
Q9C0C2
Target Species
Human
Target Name
TNKS1BP1
Target Full Name
182 kDa tankyrase-1-binding protein
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
Target Tissue Specificity
Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.
Target Synonyms
182 kDa tankyrase 1 binding protein; 182 kDa tankyrase-1-binding protein; FLJ45975; KIAA1741; TAB182; Tankyrase 1 binding protein 1 182 kDa; Tankyrase 1 binding protein 1; Tankyrase 1 binding protein of 182 kDa; TB182_HUMAN; Tnks1bp1
Target Background
Enables ankyrin repeat binding activity and enzyme binding activity. Involved in cellular response to ionizing radiation; double-strand break repair; and positive regulation of protein phosphorylation. Located in several cellular components, including actin cytoskeleton; adherens junction; and heterochromatin. Part of CCR4-NOT complex.
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