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The antibody against TNMD was raised in rabbit using the Recombinant Human Tenomodulin protein (131-254AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against TNMD was raised in rabbit using the Recombinant Human Tenomodulin protein (131-254AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-09364A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TNMD |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tenomodulin protein (131-254AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2S6 |
Uniprot Id
Q9H2S6
Target Species
Human
Target Name
TNMD
Target Full Name
Tenomodulin
Target Function
May be an angiogenesis inhibitor.
Target Subcellular Location
[Isoform 1]: Membrane; Single-pass type II membrane protein. Nucleus envelope.; [Isoform 2]: Membrane; Single-pass type II membrane protein. Nucleus envelope.; [Isoform 3]: Cytoplasm.
Target Protein Families
Chondromodulin-1 family
Target Tissue Specificity
Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.
Target Synonyms
BRICD4; BRICHOS domain containing 4; CHM1 LIKE; ChM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TeM; Tendin; Tenomodulin; Tenomodulin protein; Tnmd; TNMD_HUMAN; UNQ771/PRO1565
Target Background
This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.
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