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Rabbit anti-Human TNNC2 Polyclonal Antibody

The antibody against TNNC2 was raised in rabbit using the Recombinant Human Troponin C, skeletal muscle protein (1-160AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-40379A

The antibody against TNNC2 was raised in rabbit using the Recombinant Human Troponin C, skeletal muscle protein (1-160AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-40379A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTNNC2
Target SynonymsTNNC2 antibody; Troponin C antibody; skeletal muscle antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Troponin C, skeletal muscle protein (1-160AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP02585
Background Information
  • Uniprot Id

    P02585

  • Target Species

    Human

  • Target Name

    TNNC2

  • Target Full Name

    Troponin C, skeletal muscle

  • Target Function

    Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.

  • Target Protein Families

    Troponin C family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    TNNC2; Troponin C; skeletal muscle

  • Target Background

    Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.

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