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The antibody against TNS3 was raised in rabbit using the Recombinant Human Tensin-3 protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TNS3 was raised in rabbit using the Recombinant Human Tensin-3 protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using TNS3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using TNS3 Antibody at dilution of 1:1002
| Cat.No | ADC-16813A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TNS3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tensin-3 protein (1-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q68CZ2 |
Uniprot Id
Q68CZ2
Target Species
Human
Target Name
TNS3
Target Full Name
Tensin-3
Target Function
May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
Target Subcellular Location
Cell junction, focal adhesion.
Target Tissue Specificity
Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial
Target Synonyms
TEM 6; TEM6; TENS 1; TENS 3; TENS1; TENS3; TENS3_HUMAN; Tensin-3; tensin-like SH2 domain containing 1; Tensin-like SH2 domain containing protein 1; Tensin-like SH2 domain- containing protein 1; Tensin-like SH2 domain-containing protein 1; thyroid specific PTB domain protein; TNS 3; TNS3; TPP; Tumor endothelial marker 6
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