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Rabbit anti-Human TOM20 Polyclonal Antibody

The antibody against TOM20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human TOM20 (NP_055580.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-07834A

The antibody against TOM20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human TOM20 (NP_055580.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-07834A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTOM20
Target SynonymsMAS20; MOM19; TOM20; [KD Validated] TOM20FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Rat brain, 293T, Mouse brain, SH-SY5YApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human TOM20 (NP_055580.1).Target SpeciesHuman
Immunogen SequenceMVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGEYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVEUniprot IDQ15388
Background Information
  • Uniprot Id

    Q15388

  • Target Species

    Human

  • Target Name

    TOMM20

  • Target Full Name

    Mitochondrial import receptor subunit TOM20 homolog

  • Target Function

    Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.

  • Target Subcellular Location

    Mitochondrion outer membrane; Single-pass membrane protein.

  • Target Protein Families

    Tom20 family

  • Target Synonyms

    KIAA0016; MAS20; MGC117367; Mitochondrial 20 kDa outer membrane protein; Mitochondrial import receptor subunit TOM20 homolog; MOM19; Outer mitochondrial membrane receptor Tom20; TOM20; TOM20_HUMAN; TOMM20; Translocase of outer mitochondrial membrane 20 homolog (yeast); Translocase of outer mitochondrial membrane 20 homolog type II

  • Target Background

    Enables protein-transporting ATPase activity and unfolded protein binding activity. Involved in protein targeting to mitochondrion. Located in mitochondria-associated endoplasmic reticulum membrane and mitochondrial outer membrane.

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