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The antibody against TPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03918A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TPK1 |
| Target Synonyms | PP20; HTPK1; THMD5; TPK1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H3S4 | Immunogen Sequence |
Uniprot Id
Q9H3S4
Target Species
Human
Target Name
TPK1
Target Full Name
Thiamine pyrophosphokinase 1
Target Function
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.
Target Involvement
Thiamine metabolism dysfunction syndrome 5, episodic encephalopathy type (THMD5)
Target Protein Families
Thiamine pyrophosphokinase family
Target Tissue Specificity
Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues.
Target Research Area
others
Target Synonyms
hTPK1; Placental protein 20; PP20; Thiamin pyrophosphokinase 1; Thiamine diphosphokinase; Thiamine kinase; Thiamine pyrophosphokinase 1; THMD5; TPK1; TPK1_HUMAN
Target Background
The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5.
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