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The antibody against TRABD2B was raised in rabbit using the Recombinant Human Metalloprotease TIKI2 protein (195-405AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
The antibody against TRABD2B was raised in rabbit using the Recombinant Human Metalloprotease TIKI2 protein (195-405AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, Antigen affinity purified.
$299.00
| Cat.No | ADC-01543A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRABD2B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Metalloprotease TIKI2 protein (195-405AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A6NFA1 |
Uniprot Id
A6NFA1
Target Species
Human
Target Name
TRABD2B
Target Full Name
Metalloprotease TIKI2
Target Function
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
TIKI family
Target Synonyms
TRABD2B; HKAT; TIKI2; Metalloprotease TIKI2; EC 3.4.-.-; Heart; kidney and adipose-enriched transmembrane protein homolog; TRAB domain-containing protein 2B
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