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The antibody against TRDN was raised in rabbit using the Recombinant Human Triadin protein (75-161AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against TRDN was raised in rabbit using the Recombinant Human Triadin protein (75-161AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-02902A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRDN |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Triadin protein (75-161AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13061 |
Uniprot Id
Q13061
Target Species
Human
Target Name
TRDN
Target Full Name
Triadin
Target Function
Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
Target Involvement
Ventricular tachycardia, catecholaminergic polymorphic, 5, with or without muscle weakness (CPVT5)
Target Subcellular Location
Cell membrane. Sarcoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Synonyms
dJ166D18.1; DKFZp779I2253; MGC88285; OTTHUMP00000040354; TDN; TRDN; TRDN_HUMAN; Triadin; TRISK 51; TRISK; TRISK51
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